Apoptotic, cytotoxic, antioxidant, and antibacterial activities of biosynthesized silver nanoparticles from nettle leaf

Dağlıoğlu Y., Öztürk B. Y., Khatami M.

Microscopy Research and Technique, vol.86, no.6, pp.669-685, 2023 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 86 Issue: 6
  • Publication Date: 2023
  • Doi Number: 10.1002/jemt.24306
  • Journal Name: Microscopy Research and Technique
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, CAB Abstracts, Communication Abstracts, EMBASE, MEDLINE, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Page Numbers: pp.669-685
  • Keywords: antibacterial activity, anticancer activity, antioxidant activity, silver nanoparticles, Urtica dioica, MINIMUM QUANTITY LUBRICATION, ZINC-OXIDE NANOPARTICLES, ANTIFUNGAL ACTIVITY, GOLD NANOPARTICLES, GREEN SYNTHESIS, VEGETABLE-OIL, NANOFLUID, EXTRACT, CU, EFFICIENT
  • Eskisehir Osmangazi University Affiliated: Yes


Here, we reported the biosynthesis of silver nanoparticles (AgNPs) using Urtica dioica (nettle) leaf extract as green reducing and capping agents and investigate their anticancer and antibacterial, activity. The Nettle-mediated biosynthesized AgNPs was characterized by UV–Vis a spectrophotometer. Their size, shape and elemental analysis were determined with the using of SEM and TEM. The crystal structure was determined by XRD and the biomolecules responsible for the reduction of Ag+ were determined using FTIR analysis. Nettle-mediated biosynthesis AgNPs indicated strong antibacterial activity against pathogenic microorganisms. Again, the antioxidant activity of AgNPs is quite high when compared to ascorbic acid. Anticancer effect of AgNPs, IC50 dose was determined by XTT analysis using MCF-7 cell line and the IC50 value was found to be 0.243 ± 0.014 μg/mL (% w/v).