Effect of omentin on cardiovascular functions and gene expressions in isolated rat hearts


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Kutlay O., Kaygisiz Z., Kaygısız B.

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.21, pp.91-97, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21
  • Publication Date: 2019
  • Doi Number: 10.14744/anatoljcardiol.2018.52333
  • Journal Name: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.91-97
  • Keywords: cyclic GMP, endothelial nitric oxide synthase, heart contractility, L-type Ca2+ channel, omentin, NITRIC-OXIDE SYNTHASE, DOWN-REGULATION, ADIPOSE-TISSUE, AKT, ADIPOCYTOKINE, PHOSPHOINOSITIDE-3-KINASE-GAMMA, IDENTIFICATION, DEPENDENCE, PRESSURE, MYOCYTES
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: Omentin is a recently identified novel adipocytokine mainly expressed in the epicardial adipose tissue. Although it has favorable effects on cardiovascular disease, the impact of omentin on the hearts is still an understudied issue. The aim of the present study was to investigate the possible effects of omentin on isolated rat heart.